Gabaergic drugs list

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Actual: The potential use of GABAergic drugs in the treatment of asthma. Future Med. Chem. 3(2), 145 147 (2024). 2 Limon A, Reyes Ruiz JM, Miledi R. GABAergic drugs and Alzheimer s disease. Future Med. Chem. 3(2), 149 153 (2024). 3 Froestl W. An historical perspective on GABAergic drugs. Future Med. Chem. 3(2), 163 175 (2024).
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The author erroneously stated: Gabapentin (Neurontin) and GABAergic medications, including benzodiazepines and the Z-drug

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Effects of GABAergic drugs on the GABA turnover in the substantia nigra and the corpus striatum of the rat. Journal

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GABAergic drugs, such as clonazepam, gabapentin, and valproate

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I want to make it clear that this is a table for GABAergic nootropics, not GABAergic drugs or pharmaceuticals (like strong benzodiazepines which act as potent PAMs and cause fast tolerance build-up). Many GABAergics can impair cognitive functions thus it is imperative that the compounds suggested are also nootropics.

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According to wikipedia Gabapentin is not directly gabaergic, but it's gabaergic properties come from indirect modulation/increased

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According to wikipedia Gabapentin is not directly gabaergic, but it's gabaergic properties come from indirect modulation/increased

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GABA Agents Accession Number DBCAT Description. Substances used for their pharmacological actions on GABAergic systems. GABAergic agents include agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function. Drugs

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The potential use of GABAergic drugs in the treatment of asthma. Future Med. Chem. 3(2), 145 147 (2024). 2 Limon A, Reyes Ruiz JM, Miledi R. GABAergic drugs and Alzheimer s disease. Future Med. Chem. 3(2), 149 153 (2024). 3 Froestl W. An historical perspective on GABAergic drugs. Future Med. Chem. 3(2), 163 175 (2024).

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In molecular biology and physiology, something is GABAergic or GABAnergic if it pertains to or affects the neurotransmitter gamma-aminobutyric acid (GABA). For example, a synapse is GABAergic if it uses GABA as its neurotransmitter, and a GABAergic neuron produces GABA.

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