Nitroprusside cyanide toxicity

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Actual: Nitroprusside Induced Cyanide Toxicity. Molecule: 5 cyanide radicals, gradually released, occasionally produce cyanide or thiocyanate
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Infants are particularly susceptible to cyanide toxicity. If signs of cyanide toxicity appear: Discontinue sodium nitroprusside infusion. Consult Poisons

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Sodium nitroprusside and cyanide poisoning. Nitroprusside and cyanide toxicity. Sodium nitroprusside is a medication used in the management of acute

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by JP Rindone 2024 Cited by 77Treatment of cyanide toxicity requires the cessation of nitroprusside and, for severe toxicity, use of the cyanide antidote kit. Cyanide toxicity from

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Sodium nitroprusside and cyanide: comparative toxicity The authors review 48 references from the literature and conclude that the use of Sodium Nitroprusside

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Cyanide and nitroprusside toxicity Cyanide toxicity causes lactic acidosis by disabling the electron transport chain of oxidative

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Nitroprusside Cyanide Toxicity is due to the cyanide groups released from metabolism of the nitroprusside molecule. After gaining an electron from the iron moiety of hemoglobin, the sodium nitroprusside produces an unstable radical and methemoglobin.

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Nitroprusside: Nitroprusside is metabolized to cyanide, and it can lead to cyanide toxicity. Toxicity can appear as little as four hours after initiation of infusion. Potential risk factors for the development of toxicity are underlying renal impairment, prolonged treatment period (over 48 hours), and the utilization of a higher dose.

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Cyanide toxicity is a rare complication of sodium nitroprusside that can be difficult to diagnose in critically ill patients. We describe a case of cyanide toxicity after cardiac surgery that presented as lactic acidosis after discontinuation of nitroprusside.

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exposure or in a patient with suspicion of cyanide toxicity (eg: Unexplained, Prevention of Nitroprusside Induced Cyanide Toxicity.

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