Methadone peak and trough levels

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Actual: What do peak and trough levels indicate? Peak and trough levels indicate drug levels in an individual s body. A peak is the highest level of a medication in the blood, while a trough level indicates the lowest concentration. Troughs of medication concentration occur after the drug has been broken down and metabolized by the body.
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Test Code MDNS Methadone and Metabolites, Serum. Important Note. When drawing for a Methadone Peak and Trough. Trough is drawn Prior to the Dose of Methadone.

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The peak (highest levels) are tested for about 3–4 hours after dosing, when methadone levels peak in the body. The trough (lowest levels) are

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by S Crettol 2024 Cited by 283methadone blood levels and peak-to-trough methadone plasma level ratios, as Influence of CYP2C9 genotype on methadone plasma concentrations and peak-to-trough

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by JJ McCarthy 2024 Cited by 17Key Words: biochemical phenotype, methadone dosing, methadone metabolism, methadone peak/trough serum level, methadone/ metabolite ratio. (J

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by JJ McCarthy 2024 Cited by 17Key Words: biochemical phenotype, methadone dosing, methadone metabolism, methadone peak/trough serum level, methadone/ metabolite ratio. (J

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Methadone dose, peak, and trough blood levels covered a 24-hour cycle, obtained during stable, postinduction methadone maintenance. Results: Methadone doses showed moderately strong correlation with 3-hour postdosing peak levels, but not with the 24-hour trough level.

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Test Code MDNS Methadone and Metabolites, Serum. Important Note. When drawing for a Methadone Peak and Trough. Trough is drawn Prior to the Dose of Methadone.

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Methadone dose, peak, and trough blood levels covered a 24-hour cycle, obtained during stable, postinduction methadone maintenance. Methadone doses showed

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half-life and increased clearance of methadone resulting in lower methadone trough levels during pregnancy can peak analgesic effects, particularly

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