Parp inhibitor drugs

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Actual: Poly-ADP ribose polymerase inhibitors (PARP inhibitors) are a class of targeted therapy medications used to treat certain types of cancer. PARP inhibitors block
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PARP Inhibitors for Prostate Cancer. PARP inhibitors work best on prostate cancers that have changes, or mutations, to genes that repair damaged

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Olaparib (Lynparza) belongs to a class of drugs called PARP inhibitors. It was the first PARP inhibitor approved for ovarian cancer in

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PARP inhibitors are drugs that block the DNA-repairing mechanism of PARP. By preventing PARP from repairing the damaged DNA within cancer cells, PARP inhibitors can help kill them.

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A class of drugs that gained a lot of attention in ovarian cancer over the last 10 years are PARP inhibitors. PARP inhibitors are an oral

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They target PARP, or poly (ADP These advancements will help solidify PARP inhibitors as a foundational class of cancer drugs, says Litton.

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PARP inhibitors are drugs that block the PARP within cells. Disabling PARP in cancer cells prevents the cell from repairing its DNA and causes the cell to die. PARP inhibitors are oral drugs that

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PARP inhibitors like olaparib (Lynparza) and talazoparib (Talzenna). These drugs stop a protein known as poly-ADP ribose polymerase (PARP) from

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Importantly, these two PARP inhibitors are metabolised to varying degrees by specific CYPs, leading to a unique set of drug-drug interactions for each PARP inhibitor. These interactions occur because of cytochrome enzyme inhibition or induction.

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PARP inhibitors are drugs that block the PARP within cells. Disabling PARP in cancer cells prevents the cell from repairing its DNA and causes the cell to die. PARP inhibitors are oral drugs that

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