Antimetabolite and antimitotic drugs can be used to treat hypertrophic scars and keloids while also mitigating their likelihood of recurrence.
It is therefore essential, in the development of novel treatments, that the mechanism(s) underlying cellular cytotoxicity in antimitotic drugs be determined. P-glycoprotein (P-gp) is a component of the cellular membrane that expels antimitotic drugs and its overexpression is one of the major mechanisms of MDR [4,5,6].
antimitotic drugs like paclitaxel, resulting in multinucleation and delayed cell death . Furthermore, in the presence of mutations in DNA
Drugs The content in the video is Pharmacology - Chemotherapy agents (MOA, Alkalating, antimetabolites, topoisomerase, antimitotic ).
AXL inhibition sensitizes mesenchymal cancer cells to antimitotic drugs AXL inhibition sensitizes mesenchymal cancer cells to antimitotic drugs. more
Antimetabolite and antimitotic drugs can be used to treat hypertrophic scars and keloids while also mitigating their likelihood of recurrence.
We conclude that variation in sensitivity to antimitotic drugs in drug-naive cell lines is governed more by differences in apoptotic signaling
The antimitotic drugs such as colchicine, podophyllotoxin, etc. are currently believed to exert their cytotoxic and antimitotic effects due to binding of the
antimitotic drugs available at the time. This was an extraordinary drugs to overcome drug resistance in tissue culture. Researchers
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