How Much Does Lisinopril Lower Blood Pressure? The aim of ACE inhibitors like lisinopril is to lower your blood pressure to the target range.
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How does hydrochlorothiazide work (mechanism of action)? Hydrochlorothiazide works by increasing how much you pee. It does this by helping the kidneys remove electrolytes, such as sodium (salt), and water from the body. It also appears to allow blood to flow more freely (less resistance to flow), which may help with lowering blood pressure.
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