Allopurinol dose renal

4 Allopurinol dose needs to be adjusted in renal failure. Maximum daily dose of allopurinol is 800 mg/day. Dose adjustments may be necessary if allopurinol

Allopurinol. Allopurinol has a renally excreted active metabolite that accumulates in renal impairment and may cause adverse effects if the dose is not adjusted

Alternatively, colchicine Lowering the starting dose of allopurinol appropriate to the level of renal function reduces the risk of allopurinol.

Allopurinol. Allopurinol has a renally excreted active metabolite that accumulates in renal impairment and may cause adverse effects if the dose is not adjusted

maximum dose of allopurinol (3) maximum dose of allopurinol in the UK is 900 mg daily. However, the maximum permitted dose of allopurinol is lower in the presence of impaired renal function, determined by the degree of impairment. In severe renal failure, allopurinol should be commenced at the lower dose of 50 mg daily and increased in 50 mg

Alternatively, colchicine Lowering the starting dose of allopurinol appropriate to the level of renal function reduces the risk of allopurinol.

Allopurinol. Allopurinol has a renally excreted active metabolite that accumulates in renal impairment and may cause adverse effects if the dose is not adjusted

Allopurinol. Allopurinol has a renally excreted active metabolite that accumulates in renal impairment and may cause adverse effects if the dose is not adjusted

renal function, the advice given in Dosage in renal impairment A reduction in the dose of allopurinol is therefore required in patients with