Granulocyte colony stimulating factor drugs

by JR Schriber 2024 Cited by 23The colony-stimulating factors (CSFs) have emerged as effective drugs in a variety of clinical situations Granulocyte Colony-Stimulating Factor / adverse

Granulocyte Colony Stimulating Factor is a growth factor that stimulates the bone marrow to produce white blood cells. These cells protect the

L03AAColony stimulating factors. Drugs. Drug, Drug Description. Sargramostim, A modified form of recombinant human granulocyte-macrophage colony stimulating

1. Granulocyte Colony-Stimulating Factor (G-CSF) Granulocyte colony-stimulating factor (G-CSF) is a glycoprotein first recognized for its ability to facilitate the formation of neutrophilic granulocyte colonies in soft agar from bone marrow cells [1, 2]. Endogenous production of G-CSF is largely stimulated by infection and tissue damage.

Granulocyte Colony-Stimulating FactorsDrugTargetTypePegfilgrastimNeutrophil elastaseenzymeLenograstimGranulocyte colony-stimulating factor receptortargetLipegfilgrastimGranulocyte colony-stimulating factor receptortargetEflapegrastimGranulocyte colony-stimulating factor receptortarget4 more rows

White blood cell growth factors Granulocyte colony stimulating factor (G-CSF, filgrastim, or Neupogen) and granulocyte macrophage-colony

Granulocyte colony-stimulating factor (G-CSF or GCSF), also known as colony-stimulating factor 3 (CSF 3), is a glycoprotein that stimulates the bone marrow to produce granulocytes and stem cells and release them into the bloodstream. [5][6] Functionally, it is a cytokine and hormone, a type of colony-stimulating factor, and is produced by a

Granulocyte Colony-Stimulating Factor is a hemopoietic drug. It is used to treat chemotherapy-induced neutropenia, fever and infections.

Granulocyte colony stimulating factor (G-CSF) and granulocyte-macrophage colony stimulating factor (GM-CSF) are glycosylated polypeptides that induce an increase in the proliferation and maturation of white blood cells including neutrophils and monocytes-macrophages. Recombinant forms of these colony stimulating factors are used to treat severe neutropenia in patients receiving cancer