Clindamycin is a substrate of CYP3A4 and to a lesser extent, CYP3A5. It is a moderate inhibitor of CYP3A4. Drugs that inhibit CYP3A5 or CYP3A4 may cause increased blood concentrations of clindamycin. CYP3A4 or 3A5 inducers may decrease plasma concentrations of clindamycin.
Clindamycin is a substrate of CYP3A4 and to a lesser extent, CYP3A5. It is a moderate inhibitor of CYP3A4. Drugs that inhibit CYP3A5 or CYP3A4 may cause increased blood concentrations of clindamycin. CYP3A4 or 3A5 inducers may decrease plasma concentrations of clindamycin.
Clindamycin is a substrate of CYP3A4 and to a lesser extent, CYP3A5. It is a moderate inhibitor of CYP3A4. Drugs that inhibit CYP3A5 or CYP3A4 may cause increased blood concentrations of clindamycin. CYP3A4 or 3A5 inducers may decrease plasma concentrations of clindamycin.
Drug interactions of Norco vs. tramadol. Norco and tramadol are processed in the liver by the CYP3A4 enzyme. CYP3A4 inhibitors and CYP3A4
Clindamycin is a substrate of CYP3A4 and to a lesser extent, CYP3A5. It is a moderate inhibitor of CYP3A4. Drugs that inhibit CYP3A5 or CYP3A4 may cause increased blood concentrations of clindamycin. CYP3A4 or 3A5 inducers may decrease plasma concentrations of clindamycin.
Studies have shown that drugs that induce CYP3A4 can decrease tadalafil exposure. CYP3A4 (e.g, Rifampin) Rifampin (600 mg daily), a CYP3A4 inducer, reduced
Drug interaction overview. CYP3A4 substrate (major); shows induction and time-dependent inhibition of CYP3A4. Strong CYP3A4 inhibitors. Decrease avacopan dose
impairment. Strong drug interaction profile CYP3A4 Inhibition: Increases levels of CYP3A4-metabolized drugs, risking toxicity.
Alprazolam is primarily metabolized by CYP3A4 and commonly associated with more drug-drug interactions than lorazepam. Inhibitors of CYP3A4 like
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