Ivermectin vs metronidazole

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Actual: Both ivermectin and metronidazole significantly improved patient erythema after 1 month of treatment, but no difference was found between metronidazole and ivermectin over the 3-month course (change in CEA of metronidazole vs ivermectin: 1.07 vs 1.04, p = 0.782 (Table II); the negative sign denotes improvement compared with baseline).
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Both ivermectin and metronidazole significantly improved patient erythema after 1 month of treatment, but no difference was found between metronidazole and ivermectin over the 3-month course (change in CEA of metronidazole vs ivermectin: 1.07 vs 1.04, p = 0.782 (Table II); the negative sign denotes improvement compared with baseline).

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There was no difference between metronidazole 0.75% and metronidazole 1% [RR, 0.64 (CI, 0.26 to 1.6)]. The direct and indirect RRs showed no incoherence for the comparison of metronidazole 0.75% vs. ivermectin, ivermectin vs. placebo, metronidazole 0.75% vs. placebo, and minocycline 3% vs. minocycline 1.5% (Supplementary Figure S2A).

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