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Author: Admin | 2025-04-28
Body. The risk is higher when Zofran is combined with other medications that also affect serotonin levels, such as lithium, antidepressants, and migraine medications. Symptoms of serotonin syndrome include sweating, fast heartbeat, nausea and vomiting, muscle spasms, muscle stiffness, blurred vision, confusion, and fever. Seek emergency medical attention if you develop these symptoms while on Zofran.Heart rhythm problemsHigh doses of ondansetron (Zofran) can increase the risk of heart rhythm problems (arrhythmias), especially in people with congenital long QT syndrome, a history of QT prolongation, congestive heart failure, low potassium or magnesium, and patients taking other drugs that can cause heart rhythm problems. Tell your healthcare provider if you have any heart rhythm abnormalities before starting ondansetron. Call your doctor without delay if you develop chest pain or a fast heartbeat, slow heartbeat, or irregular heartbeat.Masking of intestinal blockage symptomsTaking ondansetron to treat nausea and vomiting after abdominal surgery or chemotherapy can mask the symptoms of intestinal blockage and abdominal bloating. Tell your healthcare provider if you are not passing gas or stools. Check out our blog, “13 Common Chemotherapy Side Effects.”Risk in people with phenylketonuriaPeople with a rare disorder called phenylketonuria cannot break down an amino acid called phenylalanine. High levels of phenylalanine in the body can cause serious health problems. The orally disintegrating tablet of ondansetron (Zofran ODT) contains phenylalanine. Do not take Zofran ODT if you have phenylketonuria (PKU).Tips on the safe use of ondansetron (Zofran)Give your doctor or pharmacist a complete list of your medications, including prescription drugs, over-the-counter medicines, dietary supplements, and herbal remedies. This can help avoid dangerous drug interactions between ondansetron and another prescription medication or OTC product.You can take ondansetron with or without food.If you are taking the disintegrating tablet of Zofran, remove the foil backing with dry hands and immediately place the tablet under your tongue.Besides common side effects of ondansetron, like headache, tiredness, diarrhea, and constipation, this medicine can also cause dizziness. Do not drive or operate machinery until you know how ondansetron affects you. Drinking alcohol can make these side effects worse.In case of a missed dose, take your Zofran dose as soon as you remember. If it is time for the next dose, skip the missed dose and take the next dose according to the prescribed schedule. Do not take two doses to make up for a missed dose.Learn more about nausea remedies. Check out our blog “What Are the Best Medications for Nausea?”Save on Your Medication with BuzzRx!Manage your medication costs with BuzzRx coupons. Here are direct links to substantial savings for each medication:Ondansetron CouponZofran CouponLithium Carbonate CouponRemember, these coupons are widely accepted at over 60,000 pharmacies, including major chains like CVS, Walgreens, and Rite Aid. Just present
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