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Author: Admin | 2025-04-28
PATIENT INFORMATIONPAXLOVID (pax-LO-vid)(nirmatrelvir tablets; ritonavir tablets)co-packaged for oral useWhat is the most important information I should know about PAXLOVID? PAXLOVID can interact with other medicines causing severe or life-threatening side effects or death. It is important to know the medicines that should not be taken with PAXLOVID. Do not take PAXLOVID if: •you are taking any of the following medicines:oalfuzosinoamiodaroneoapalutamideocarbamazepineocolchicineodihydroergotamineodronedaroneoeletriptanoenzalutamideoeplerenoneoergotamineofinerenoneoflecainideoflibanserinoivabradine olomitapideolovastatinolumacaftor/ivacaftorolurasidoneomethylergonovineomidazolam (oral)onaloxegolophenobarbitalophenytoinopimozideoprimidoneopropafenoneoquinidine oranolazineorifampin orifapentineoSt. John’s Wort (hypericum perforatum)osildenafil (Revatio®) for pulmonary arterial hypertensionosilodosinosimvastatinotolvaptanotriazolamoubrogepantovoclosporinThese are not the only medicines that may cause serious or life-threatening side effects if taken with PAXLOVID. PAXLOVID may increase or decrease the levels of multiple other medicines. It is very important to tell your healthcare provider about all of the medicines you are taking because additional laboratory tests or changes in the dose of your other medicines may be necessary during treatment with PAXLOVID. Your healthcare provider may also tell you about specific symptoms to watch out for that may indicate that you need to stop or decrease the dose of some of your other medicines.•you are allergic to nirmatrelvir, ritonavir, or any of the ingredients in PAXLOVID. See the end of this leaflet for a complete list of ingredients in PAXLOVID. See “What are the possible side effects of PAXLOVID?” for signs and symptoms of allergic reactions.What is PAXLOVID?PAXLOVID is a prescription medicine used to treat mild-to-moderate coronavirus disease 2019 (COVID-19) in adults who are at high risk for progression to severe COVID-19, including hospitalization or death. PAXLOVID is not approved for use as pre-exposure or post-exposure treatment for prevention of COVID-19.Before taking PAXLOVID, tell your healthcare provider about all of your medical conditions, including if you:•have kidney problems. You may need a different dose or dosing schedule of PAXLOVID.•have liver problems, including hepatitis. •have Human Immunodeficiency Virus 1 (HIV-1) infection. PAXLOVID may lead to some HIV-1 medicines not working as well in the future.•are pregnant or plan to become pregnant. It is not known if PAXLOVID can harm your unborn baby. Tell your healthcare provider right away if you are or if you become pregnant.•are breastfeeding or plan to breastfeed. PAXLOVID can pass into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with PAXLOVID.Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.•Your healthcare provider can tell you if it is safe to take PAXLOVID with other medicines.•You can ask your healthcare provider or pharmacist for a list of medicines that interact with PAXLOVID. •Do not start taking a new medicine without telling your healthcare provider. Tell your healthcare provider if you are taking combined birth control (hormonal contraceptive). PAXLOVID may affect how your hormonal contraceptives work. Females who are able to become pregnant should use another effective alternative form of contraception or an additional barrier method of contraception during treatment with PAXLOVID. Talk to your healthcare provider if you have any questions about contraceptive methods that might be right for you.How should I take
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